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Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress

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Recent studies have shown that upregulation of FAO occurs predominantly in conditions of nutrient deprivation, with dual inhibition of FAO (using etomoxir) and glucose metabolism (using 2-deoxy-D-glucose [2-DG]) yielding significant benefits in animal models of glioma [123]

4.3 EMS influences GCs steroid hormone production The synthesis and secretion of steroid hormones by GCs is critical for follicular growth and, as a result, can impact the quality of oocytes